Toxic to dogs · Medications

Is Moxidectin toxic to dogs?

Extreme severity

Yes. Even a small amount can be life-threatening — treat any exposure as an emergency and contact a vet immediately.

Symptoms to watch for

  • dilated pupils
  • tremors
  • drooling
  • seizures
  • coma
  • inability to breath
  • death

How vets treat it

Aggressive veterinary treatment is required to manage neurological symptoms and support respiratory function.

Why it's dangerous

Moxidectin is an anthelmintic drug that can cross the blood-brain barrier in sensitive breeds or at high doses, leading to severe neurological impairment and respiratory failure.

Toxic compound: Moxidectin

Good to know

Certain breeds with the MDR1 gene mutation (e.g., Collies, Shepherds) are extremely sensitive. Poisoning can occur from ingesting horse dewormer or feces from recently dewormed horses.

Sources

This page is informational and is not veterinary advice. If your pet has been exposed to something risky, contact your vet or an animal poison control line right away.

More substances toxic to dogs

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