Toxic to dogs · Chemicals

Are Long-acting Anticoagulants toxic to dogs?

Extreme severity

Yes, Long-acting Anticoagulants are extremely toxic to dogs. Even a small amount can be life-threatening, so treat any exposure as an emergency and contact a vet immediately.

Symptoms to watch for

  • lethargy
  • exercise intolerance
  • coughing
  • difficulty breathing
  • weakness
  • pale gums
  • vomiting
  • diarrhea
  • nose bleeds
  • bruising
  • bloody urine
  • swollen joints
  • inappetence
  • bleeding from the gums

How vets treat it

Administration of prescription Vitamin K1 antidote, typically for 30 days, followed by a prothrombin (PT) blood clotting test 48 hours after the final dose.

Why it's dangerous

These substances prevent the blood from clotting by interfering with Vitamin K recycling, which leads to life-threatening internal bleeding.

Toxic compound: Brodifacoum, difethialone, bromadiolone, warfarin, diphacinone, chlorophacinone

Good to know

Signs of poisoning typically take 3-5 days to appear. Cats are generally more resistant than dogs. Underlying liver or GI disease increases risk.

Sources

This page is informational and is not veterinary advice. If your pet has been exposed to something risky, contact your vet or an animal poison control line right away.

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