Why it's dangerous
Ivermectin acts as an anthelmintic that can cross the blood-brain barrier in sensitive breeds or at high doses, leading to central nervous system depression and severe neurological impairment.
Toxic compound: Avermectins
Good to know
Certain breeds with the MDR1 (ABCB1) gene mutation are hypersensitive. Poisoning often occurs from horse dewormer ingestion or eating feces of recently dewormed horses.
Sources
This page is informational and is not veterinary advice. If your pet has been exposed to something risky, contact your vet or an animal poison control line right away.