Is Effexor toxic to dogs?

High severity No safe amount — No amount is considered safe.

Yes, Effexor is highly toxic to dogs. Exposure can cause serious illness and needs prompt veterinary attention. No amount is considered safe.

Symptoms to watch for

sedation
central nervous system stimulation
anorexia
lethargy
vomiting
tremoring
seizures
hyperthermia
diarrhea
abdominal pain
dilated pupils
stumbling gait
rapid heart rate
drooling

How vets treat it

Immediate veterinary attention is required for decontamination, sedation, thermoregulation, IV fluid therapy, blood pressure and ECG monitoring, and supportive care.

Why it's dangerous

These medications inhibit the re-uptake of serotonin and/or norepinephrine in the central nervous system, which can lead to excessive levels and potentially cause serotonin syndrome.

Toxic compound: venlafaxine

Good to know

Even therapeutic doses can result in moderate to severe clinical signs; rapid onset of symptoms makes professional decontamination critical.

Sources

Pet Poison Helpline

This page is informational and is not veterinary advice. If your pet has been exposed to something risky, contact your vet or an animal poison control line right away.

The StrawPaw Team · How we prepare our guides

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